PHARMACEUTICAL COMPOSITION

PROBLEM TO BE SOLVED: To provide a pharmaceutical composition containing a piperidine compound having excellent tachykinin receptor-antagonistic activities as an active ingredient. SOLUTION: The pharmaceutical composition contains the piperidine compound represented by general formula [I] or a pharm...

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Bibliographic Details
Main Authors YAMANAKA TAKESHI, MIYAKE TSUTOMU, KINO RIE, ASAI HIDETOSHI
Format Patent
LanguageEnglish
Published 25.10.2007
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PROBLEM TO BE SOLVED: To provide a pharmaceutical composition containing a piperidine compound having excellent tachykinin receptor-antagonistic activities as an active ingredient. SOLUTION: The pharmaceutical composition contains the piperidine compound represented by general formula [I] or a pharmacologically acceptable salt thereof as the active ingredient. In the formula, ring A is a benzene ring which may have a substituent; ring B is a benzene ring which may have a substituent; R1is a hydrogen atom or a substituent of an amino group; R2is a hydrogen atom, a hydroxy group which may have a substituent, or the like; Z is an oxygen atom or a group represented by -N(R3)-; R3is a hydrogen atom or an alkyl group which may have a substituent; R4aand R4bare the same or different and each a hydrogen atom or an alkyl group which may have a substituent, or a group forming an alkylene group by bonding to each other at the terminals. COPYRIGHT: (C)2008,JPO&INPIT
Bibliography:Application Number: JP20070065971