VARENICLINE STANDARD AND IMPURITY CONTROL

PROBLEM TO BE SOLVED: To provide a composition comprising varenicline or a pharmaceutically acceptable salt thereof and controlling the amount of impurities thereof. SOLUTION: The varenicline composition comprises one or more of several mononitro, monoamino, mixed aminonitro, diamino or dinitro inte...

Full description

Saved in:
Bibliographic Details
Main Authors BRONK KAREN S, SINAY TERRY G, WITHBROE GREGORY JOHN, FRANK ROBERT BUSCH
Format Patent
LanguageEnglish
Published 11.10.2007
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:PROBLEM TO BE SOLVED: To provide a composition comprising varenicline or a pharmaceutically acceptable salt thereof and controlling the amount of impurities thereof. SOLUTION: The varenicline composition comprises one or more of several mononitro, monoamino, mixed aminonitro, diamino or dinitro intermediates which are synthetic intermediates therefor at >0 to ≤about 500 ppm, ≤about 100 or ≤about 10 ppm concentration in the composition comprising the varenicline. COPYRIGHT: (C)2008,JPO&INPIT
Bibliography:Application Number: JP20070078240