5'-NUCLEOTIDASE-RESISTANT DERIVATIVE OF IMMUNOPOTENTIATING INOSINE-MONOPHOSPHATE AND USE THEREOF

PROBLEM TO BE SOLVED: To provide a 5'-nucleotidase-resistant derivative of immunopotentiating inosine-mono-phosphoric acid that has more larger immunopotentiating activity, higher stability and resistance to 5'-nucleotidase. SOLUTION: This invention relates to 5'-nucleotidase-resistan...

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Bibliographic Details
Main Authors HADDEN JOHN W, GINER SOROLLA ALFREDO, MASIHI NOEL K
Format Patent
LanguageEnglish
Published 08.03.2007
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PROBLEM TO BE SOLVED: To provide a 5'-nucleotidase-resistant derivative of immunopotentiating inosine-mono-phosphoric acid that has more larger immunopotentiating activity, higher stability and resistance to 5'-nucleotidase. SOLUTION: This invention relates to 5'-nucleotidase-resistant inosine-5'-monophosphoric acid and a method for producing the derivative and inosine-5'-monophosphoric acid is chemically changed to a compound represented by formula (I) (wherein R is selected from the group consisting of an alkyl, an alkoxy and secondary amino compound) and the biological activity of the inosine-5'-monophosphoric acid is allowed to retain in vivo. COPYRIGHT: (C)2007,JPO&INPIT
Bibliography:Application Number: JP20060330014