HETEROBIARYL DERIVATIVE AS INHIBITOR AGAINST MATRIX METALLOPROTEINASE

PROBLEM TO BE SOLVED: To provide a compound represented by formula I (wherein, R1, Q, S, T, U, V and R2are the same as those defined in the specification) or a pharmaceutically acceptable salt thereof. SOLUTION: The invention provides a medicinal composition for curing diseases such as heart disease...

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Bibliographic Details
Main Authors WILSON MICHAEL WILLIAM, MORRIS MARK ANTHONY, BUNKER AMY MAE, O'BRIEN PATRICK MICHAEL
Format Patent
LanguageEnglish
Published 02.11.2006
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PROBLEM TO BE SOLVED: To provide a compound represented by formula I (wherein, R1, Q, S, T, U, V and R2are the same as those defined in the specification) or a pharmaceutically acceptable salt thereof. SOLUTION: The invention provides a medicinal composition for curing diseases such as heart disease, multiple sclerosis, hypertrophic arthritis and rheumatoid arthritis, arthritis other than hypertrophic arthritis or rheumatoid arthritis, heart failure, inflammatory bowel disorder, heart failure, age-related macular degeneration, chronic obstructive pulmonary disease, asthma, periodontal disease, psoriasis, atherosclerosis and osteoporosis, the above composition that contains the compound represented by formula I or the pharmaceutically acceptable salt thereof in itself or in a product composition. The invention provides a combination of the compound represented by formula I or the pharmaceutically acceptable salt thereof and another pharmaceutically active component as described in the specification. COPYRIGHT: (C)2007,JPO&INPIT
Bibliography:Application Number: JP20060206738