PROLIFERATION CONTROL OF CELL ENCAPSULATED IN ARTIFICIAL ORGAN IN LIVING BODY

• Main Authors: DOHERTY EDWARD J, HOLLAND LAURA M, SCHINSTINE MALCOLM, SHOICHET MOLLY S, GENTILE FRANK T, ALBEE MESSING, HAMMANG JOSEPH P, CAIN BRIAN M, AEBISCHER PATRICK, WINN SHELLEY R
• Format: Patent
• Language: English
• Published: 03.08.2006
• Subjects: AGRICULTURE; ANIMAL HUSBANDRY; BEER; BIOCHEMISTRY; CARE OF BIRDS, FISHES, INSECTS; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; ENZYMOLOGY; FISHING; FORESTRY; HUMAN NECESSITIES; HUNTING; HYGIENE; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METALLURGY; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; NEW BREEDS OF ANIMALS; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; TRAPPING; VINEGAR; WINE

PROBLEM TO BE SOLVED: To provide a method and a composition for controlling the proliferation of an encapsulated cell which combines various advantages of a proliferating cell and a differentiated nondividing cell. SOLUTION: In the method and composition, the distribution of a cell (namely, the number of cells in a BAO or the present position of cells, or both of them) is controlled, when a cell is encapsulated in BAO. (1) The method and composition is for modifying the cells encapsulated in the BAO and (2) the composition is for modifying proliferation surface in the BAO. COPYRIGHT: (C)2006,JPO&NCIPI