NEW MONOCLONAL ANTIBODY AND UTILIZATION OF THE SAME

PROBLEM TO BE SOLVED: To provide a monoclonal antibody recognizing a protein specifically expressed in M-phase cells and also a method for labelling, collecting and detecting the M-phase cells in a high yield by using the monoclonal antibody. SOLUTION: This monoclonal antibody recognizing a regulato...

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Bibliographic Details
Main Authors KONO TOMOKANE, BOGDAN I GERASHCHENKO, HOSOYA HIROSHI, UCHIMURA TAKASHI
Format Patent
LanguageEnglish
Published 22.09.2005
Edition7
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
TESTING
VINEGAR
WINE
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Summary:PROBLEM TO BE SOLVED: To provide a monoclonal antibody recognizing a protein specifically expressed in M-phase cells and also a method for labelling, collecting and detecting the M-phase cells in a high yield by using the monoclonal antibody. SOLUTION: This monoclonal antibody recognizing a regulatory light chain of doubly phosphorylated myosin II expressed specifically in human mitotic phase cells, and a hybridoma expressing the monoclonal antibody are prepared. By using the monoclonal antibody, it is possible to label and detect the mitotic phase cells in a high accuracy, and further to collect the mitotic phase cells in a high yield. COPYRIGHT: (C)2005,JPO&NCIPI
Bibliography:Application Number: JP20040069802