ANTIBODY TARGETED AT ANTIGEN SPECIFIC TO CANCER

• Main Authors: FUKUCHI KEISUKE, AZUMA TOSHINORI, ICHIKAWA KIMIHISA, HIRAI TAKEHIRO, TAKAHASHI HIDE
• Format: Patent
• Language: English
• Published: 21.10.2004
• Edition: 7
• Subjects: APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPOSITIONS THEREOF; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; CULTURE MEDIA; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; HUMAN NECESSITIES; HYGIENE; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PHYSICS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROCESSES OF PREPARING SUCH COMPOSITIONS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; TESTING; VINEGAR; WINE

PROBLEM TO BE SOLVED: To provide a method for detecting cancer by using an oncogene, to provide a method for screening a compound having an effect of treating and/or preventing the cancer, and to provide a pharmaceutical composition for treating and/or preventing the cancer. SOLUTION: This method for detecting the cancer comprises using expression of a human oculospanin gene as an indicator. The pharmaceutical composition contains an antibody which specifically recognizes human oculospanin and has cytotoxic activity on a cancer cell. COPYRIGHT: (C)2005,JPO&NCIPI