NEW SELENYL LINKER AND ITS USE

• Main Authors: NAKAMURA KAZUHIKO, OKUNO HIROAKI, ONISHI HIROSUE, ODAKA MASATO, HORIKAWA EIJI
• Format: Patent
• Language: English
• Published: 07.10.2004
• Edition: 7
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS; TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE

PROBLEM TO BE SOLVED: To provide a means and a method for easily and efficiently synthesizing an unstable compound such as a dehydroamino acid and a dehydropeptide. SOLUTION: The subject linker is expressed by formula (I) (R1is a bivalent organic group which may contain a hetero-atom; R2is OR3or NHR3; R3is H or a protecting group selected from tert-butyl, ester methyl, ethyl, benzyl, allyl, triphenylmethyl, tert-butyloxy-carbonyl, t-amyloxycarbonyl, adamantyloxycarbonyl, 4-methoxybenzyloxycarbonyl, benzyloxycarbonyl, 2-chlorobenzyloxycarbonyl, a cycloalkyloxycarbonyl, isopropyloxycarbonyl, 9-fluorenylmethyloxycarbonyl, allyloxycarbonyl and other protecting groups). COPYRIGHT: (C)2005,JPO&NCIPI