VALIDATION DESIGN FOR MICROARRAY

• Main Authors: TUDOR JONATHAN, SCHNABEL ROLAND, CONZONE SAMUEL D, VAN DEN BROEK DIRK, SCHOLLER PATRICK
• Format: Patent
• Language: English
• Published: 15.07.2004
• Edition: 7
• Subjects: APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; BEER; BIOCHEMISTRY; CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY; CHEMISTRY; COMBINATORIAL CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES; MEASURING; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; PHYSICS; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; TESTING; THEIR RELEVANT APPARATUS; TRANSPORTING; VINEGAR; WINE

PROBLEM TO BE SOLVED: To quickly prepare a microarray, in particular, a DNA microarray validated in an industrial production scale with excellent cost efficiency. SOLUTION: A system in the present invention has at least one or more of device(s) designed to input information about a target molecule analyzed by the microarray, one device designed to determine a probe molecule interactive with the target molecule potentially based on the information about the analyzed target molecule, one lay-out providing device, one probe molecule synthesizing device designed for ex-situ synthesis for the probe molecule, and a microarray providing device designed to apply the probe molecule to a support body. The lay-out providing device comprises a device for synthesizing the test probe molecule with high density, a microarray testing device and a microarray reading device. COPYRIGHT: (C)2004,JPO&NCIPI