AST INHIBITOR

PROBLEM TO BE SOLVED: To provide a human respiratory tract trypsin-like enzyme (respiratory tract-specific trypsin-like enzyme) or AST (Airway Specific Trypsin-like Protease) inhibitor. SOLUTION: The AST inhibitor comprises an amidinonaphthyl derivative represented by a general formula (I) (wherein...

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Bibliographic Details
Main Authors TAKENOUCHI KAZUYA, EGUCHI HIROSHI, MITSUYAMA ETSUKO
Format Patent
LanguageEnglish
Published 10.09.2003
Edition7
Subjects
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Summary:PROBLEM TO BE SOLVED: To provide a human respiratory tract trypsin-like enzyme (respiratory tract-specific trypsin-like enzyme) or AST (Airway Specific Trypsin-like Protease) inhibitor. SOLUTION: The AST inhibitor comprises an amidinonaphthyl derivative represented by a general formula (I) (wherein R1, R2and R3are each hydrogen atom, a halogen atom, carboxy group, amino group, cyano group, nitro group, hydroxy group, a lower alkoxy group or a lower alkyl group or a lower alkoxycarbonyl group or the like which may be substituted; Z is a lower alkylene group or carbonyl group; n is 0 or 1), its pharmaceutically acceptable salt or its solvation product. COPYRIGHT: (C)2003,JPO
Bibliography:Application Number: JP20020049564