AST INHIBITOR

PROBLEM TO BE SOLVED: To provide an AST (Airway Specific Trypsin-like Protease) inhibitor which is clinically applicable as a prophylactic and/or therapeutic agent for chronic respiratory tract diseases. SOLUTION: The AST inhibitor comprises an amidine derivative represented by a general formula (I)...

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Bibliographic Details
Main Authors TAKENOUCHI KAZUYA, EGUCHI HIROSHI, TAKANO YASUNOBU
Format Patent
LanguageEnglish
Published 10.09.2003
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PROBLEM TO BE SOLVED: To provide an AST (Airway Specific Trypsin-like Protease) inhibitor which is clinically applicable as a prophylactic and/or therapeutic agent for chronic respiratory tract diseases. SOLUTION: The AST inhibitor comprises an amidine derivative represented by a general formula (I) (wherein R1, R2, R3and R4are each hydrogen atom or the like; n is 0-4; A is a carboxyalkyl or the like; X is oxygen atom or the like; Y is a saturated or unsaturated 5-6 membered heterocyclic group or the like which may have a substituent group; a group represented by general formula (V) is a naphthyl group or the like), its pharmaceutically acceptable salt or its solvation product. COPYRIGHT: (C)2003,JPO
Bibliography:Application Number: JP20020049565