SULFONAMIDE MATRIX METALLOPROTEINASE INHIBITOR
PROBLEM TO BE SOLVED: To provide a compound which is useful for curing cardiopathy, multiple sclerosis, osteoporosis, etc., as a matrix metalloproteinase inhibitor. SOLUTION: A compound represented by the formula [wherein R and R are each H, an alkyl or a substituted alkyl; R and R are each H, a hal...
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Main Authors | , , , , |
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Format | Patent |
Language | English |
Published |
23.10.2002
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Edition | 7 |
Subjects | |
Online Access | Get full text |
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Abstract | PROBLEM TO BE SOLVED: To provide a compound which is useful for curing cardiopathy, multiple sclerosis, osteoporosis, etc., as a matrix metalloproteinase inhibitor. SOLUTION: A compound represented by the formula [wherein R and R are each H, an alkyl or a substituted alkyl; R and R are each H, a halogen or an alkyl; X is OH or NHOH; and V is O, S, SO2 , NR (wherein R contains H or an alkyl) or CH2 ] or its salt tolerable as a medicine is provided. |
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AbstractList | PROBLEM TO BE SOLVED: To provide a compound which is useful for curing cardiopathy, multiple sclerosis, osteoporosis, etc., as a matrix metalloproteinase inhibitor. SOLUTION: A compound represented by the formula [wherein R and R are each H, an alkyl or a substituted alkyl; R and R are each H, a halogen or an alkyl; X is OH or NHOH; and V is O, S, SO2 , NR (wherein R contains H or an alkyl) or CH2 ] or its salt tolerable as a medicine is provided. |
Author | PICARD JOSEPH ARMAND SHULER KEVON RAY SLISKOVIC DRAGO ROBERT O'BRIEN PATRICK MICHAEL PATT WILLIAM CHESTER |
Author_xml | – fullname: PICARD JOSEPH ARMAND – fullname: PATT WILLIAM CHESTER – fullname: O'BRIEN PATRICK MICHAEL – fullname: SHULER KEVON RAY – fullname: SLISKOVIC DRAGO ROBERT |
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Snippet | PROBLEM TO BE SOLVED: To provide a compound which is useful for curing cardiopathy, multiple sclerosis, osteoporosis, etc., as a matrix metalloproteinase... |
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SubjectTerms | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
Title | SULFONAMIDE MATRIX METALLOPROTEINASE INHIBITOR |
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