NUCLEIC ACID CAPABLE OF PROMOTING EXPRESSION OF GENE

PROBLEM TO BE SOLVED: To obtain a nucleic acid related to a rise in expression of a gene, especially the nucleic acid capable of promoting the production of a transcriptional product from the gene and promoting the production of a translational product therefrom and an expression vector, etc., of an...

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Bibliographic Details
Main Author HARA TOSHIO
Format Patent
LanguageEnglish
Published 25.09.2001
Edition7
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Summary:PROBLEM TO BE SOLVED: To obtain a nucleic acid related to a rise in expression of a gene, especially the nucleic acid capable of promoting the production of a transcriptional product from the gene and promoting the production of a translational product therefrom and an expression vector, etc., of an SF2 type HIVgp120 expressed by using the nucleic acid. SOLUTION: This nucleic acid is capable of inducing or promoting the expression of a gene and is a secretory signal sequence of a chicken lysozyme or a secretory signal sequence of an SF162 type HIVgp120. When the SF2 type HIVgp120 has an intrinsic signal sequence, it is difficult to artificially express the gene. The expression thereof, however, can be induced by replacing the intrinsic signal sequence with the two secretory signal sequences.
Bibliography:Application Number: JP20000078897