ASSAY METHOD

PROBLEM TO BE SOLVED: To provide an assay method for determining whether an agent can regulate the interaction of CCR5 and gp 120. SOLUTION: The agent is inculated along with CCR5 and gp 120 to form a first reaction mixture and it is determined whether the agent regulates the interaction of CCR5 and...

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Bibliographic Details
Main Authors PERROS MANOUSSOS, RICKETT GRAHAM ANTHONY, DOBBS SUSAN
Format Patent
LanguageEnglish
Published 21.09.2001
Edition7
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
TESTING
VINEGAR
WINE
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Summary:PROBLEM TO BE SOLVED: To provide an assay method for determining whether an agent can regulate the interaction of CCR5 and gp 120. SOLUTION: The agent is inculated along with CCR5 and gp 120 to form a first reaction mixture and it is determined whether the agent regulates the interaction of CCR5 and gp 120 and, herein, gp 120 is associated with CD4. Especially, the interaction is a low affinity bond.
Bibliography:Application Number: JP20010003426