ANTICOAGULANT COMPOSITION AND ITS MANUFACTURE

PROBLEM TO BE SOLVED: To prevent hemolyzation from occurring when mixed with blood by combining an anticoagulant with a binder for making solid. SOLUTION: The composition can be obtained by drying a solution with a pH of for example 5-10 containing an anticoagulant and a binder for preventing blood...

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Bibliographic Details
Main Authors AKAI YASUMASA, NISHIZAKI MIKIKO
Format Patent
LanguageEnglish
Published 14.09.2000
Edition7
Subjects
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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Summary:PROBLEM TO BE SOLVED: To prevent hemolyzation from occurring when mixed with blood by combining an anticoagulant with a binder for making solid. SOLUTION: The composition can be obtained by drying a solution with a pH of for example 5-10 containing an anticoagulant and a binder for preventing blood from being coagulated. The anticoagulant is selected from a group consisting of a calciumchelate agent, a thrombin inhibitor, and a protein synthesis inhibitor and is used in concentration for preventing the blood from being coagulated. The binder includes gelatin, carboxymethylcellulose, or the like, and polyvinylalcohol is preferable among them. Also, a drying method includes vacuum drying, hot-air drying, or the like. Among them, freezing drying and atomizing drying are preferable, where the atomizing drying is most preferable since it can efficiently prevent hemolyzation.
Bibliography:Application Number: JP19990056219