DERIVATI DELLA [1,3] OSSAZINO [4,3A] ISOCHINOLINA, PROCEDIMENTO PER LA LORO PREPARAZIONE E COMPOSIZIONI FARMACEUTICHE CHE LI CONTENGONO

The invention relates to new [1,3]oxazino[4,3-a]-isoquinoline derivatives of the formula (I) (I) wherein R1 and R2 represent hydroxyl or alkoxy having from 1 to 6 carbon atoms, R3 is hydrogen, alkyl having from 1 to 8 carbon atoms, cycloakyl or cycloalkenyl having from 3 to 6 carbon atoms, optionall...

Full description

Saved in:
Bibliographic Details
Main Authors LASZLO DENES, LASZLO SZPORNY, JENO KOBOR, ELEMER EZER, EVA PALOSI, PAL PERJESI, GABOR BERNATH, GYORGY HAJOS, FERENC FULOP, PAL SOHAR
Format Patent
LanguageItalian
Published 25.10.1984
Edition3
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:The invention relates to new [1,3]oxazino[4,3-a]-isoquinoline derivatives of the formula (I) (I) wherein R1 and R2 represent hydroxyl or alkoxy having from 1 to 6 carbon atoms, R3 is hydrogen, alkyl having from 1 to 8 carbon atoms, cycloakyl or cycloalkenyl having from 3 to 6 carbon atoms, optionally substituted phenyl, aralkyl having from 1 to 4 carbon atoms in the alkyl moiety or heteroaryl, R4 is hydrogen or alkyl having from 1 to 4 carbon atoms, or R3 and R4 together form a -(CH2)n- group, in which n is an integer from 3 to 7, R5 is hydroxyl, halogen or an group, in which R6 is optionally substituted phenyl, X is oxygen or sulfur, and salts thereof. According to another aspect of the invention there is provided a process for the preparation of these compounds. Compounds of formula (I) are pharmaceutically active. Pharmaceutical compositions containing them are also within the scope of the invention.
Bibliography:Application Number: IT19840023305