DERIVATI DELLA AZEPINO 1 2 A PIRIMIDINA AD AZIONE BRONCODILATATRICE E RELATIVI SALI DI ADDIZIONE CON ACIDI E COMPOSIZIONI FARMACEUTICHE CHELI CONTENGONO

The invention relates to new azepino[1,2-a]pyrimidine derivatives-of the general formula I wherein p=1, 2 and acid addition salts thereof which can be prepared by (a) reacting a compound of the formula II with a compound of the general formula III wherein p is as defined above and R7 is alkoxycarbon...

Full description

Saved in:
Bibliographic Details
Main Authors TIBOR BREINING, JOZSEF KOKOSI, ISTVAN HERMECZ, LELLE VASVARI NATA DEBRECZY, AGNES HORVATH SANDOR VIRAG
Format Patent
LanguageItalian
Published 31.10.1983
Edition3
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:The invention relates to new azepino[1,2-a]pyrimidine derivatives-of the general formula I wherein p=1, 2 and acid addition salts thereof which can be prepared by (a) reacting a compound of the formula II with a compound of the general formula III wherein p is as defined above and R7 is alkoxycarbonyl containing 2 to 5 carbon atoms or carboxamido or (b) reacting a compound of the general formula IV wherein R8 is alkyl containing 1 to 4 carbon atoms with a compound of the general formula V wherein R7 is as defined above and if desired converting a compound of the general formula I to acid addition salt thereof or setting it free from the salt thereof. The new compounds show bronchodilatory activity.
Bibliography:Application Number: IT19830068136