METODO PER LA DETERMINAZIONE DI ANTICORPO ANTISTREPTOLISINA O

• Main Authors: ARAI KENJI, KAGIMOTO YOSHITAKA
• Format: Patent
• Language: Italian
• Published: 27.10.1997
• Edition: 4
• Subjects: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PHYSICS; TESTING

A method for immunologically determining antistreptolysin O antibody comprises contacting a test sample solution containing antistreptolysin O antibody with a binding agent to selectively bind the antistreptolysin O antibody to the binding agent, and determining an amount of the bound antistreptolysin O antibody, wherein the binding agent comprises a streptolysin O-immobilized carrier obtained by contacting a solution containing streptolysin O with a carrier having immobilized thereon at least one steroid represented by formula (1): (1) wherein R1 is a side chain moiety of cholesterol or a side chain moiety of cholic acid, wherein each of the side chain moieties is independently unsubstituted or substituted and independently saturated or unsaturated; R2 is hydrogen or hydroxyl; and each dashed line independently represents a single bond or no bond. The method of the present invention can be used for determining antistreptolysin O antibody specifically, accurately and easily and can be practiced not only by manual operation but also by automated operation.