Process for the preparation of triazolyl isopropanols, in particular fluconazole

An improved method is described for the synthesis of fluconazole by reaction of a halohydrin intermediate with 4- amino-1,2,4-triazole with subsequent deamination with nitrous acid.

Saved in:
Bibliographic Details
Main Authors BENIGNI FULVIO, PRENDIN RINO
Format Patent
LanguageEnglish
Italian
Published 20.02.1995
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

More Information
Summary:An improved method is described for the synthesis of fluconazole by reaction of a halohydrin intermediate with 4- amino-1,2,4-triazole with subsequent deamination with nitrous acid.
Bibliography:Application Number: IT19900020586