COMPOSIZIONI FARMACEUTICHE LAMINATE TRANSDERMALI AD EFFETTO PROLUNGATO E PROCEDIMENTO PER LA LORO PREPARAZIONE
The invention relates to a transdermal laminated pharmaceutical composition (plaster) having prolonged effect, wherein one or more storing layer(s) comprising the active ingredient, an ethylene/vinyl acetate copolymer regulating layer and an adhesive layer are applied onto the carrier. The pharmaceu...
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Main Authors | , , , , |
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Format | Patent |
Language | Italian |
Published |
12.09.1990
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Edition | 5 |
Subjects | |
Online Access | Get full text |
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Summary: | The invention relates to a transdermal laminated pharmaceutical composition (plaster) having prolonged effect, wherein one or more storing layer(s) comprising the active ingredient, an ethylene/vinyl acetate copolymer regulating layer and an adhesive layer are applied onto the carrier. The pharmaceutical composition is prepared by coupling a carrier comprising the active ingredient with a regulating layer consisting of an ethylene/vinyl acetate copolymer foil having a vinal acetate content of 2-40 molar %. The foil is previously irradiated in a thickness of 100-300 mu m with a high-energy irradiation in a dose of 1-15 Mrad-preferably with electrone radiation-and thereafter stretched at 80 DEG -90 DEG C. to a thickness of 2-200 mu m. The system comprising the carrier and the regulating layer is subsequently coupled with an adhesive layer. |
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Bibliography: | Application Number: IT19870022032 |