DERIVATI DELLA GONADO-LIBERINA CONTENENTI UN GRUPPO BETA-ASPARTILE,PROCEDIMENTO PER LA LORO PREPARAZIONE E PREPARAZIONI FARMACEUTICHE CHE LI CONTENGONO

The invention relates to novel gonadoliberine derivatives of the general formula (I) (I) wherein X represents an -O-R group wherein R is a benzyl group or a C1-4 alkyl group, an group wherein R1 and R2 independently stand for hydrogen, a C1-5 alkyl, aryl, aryl-C1-2-alkyl, morpholino, 1-indolinyl or...

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Bibliographic Details
Main Authors SEPRODI JANOS, ERCHEGYI JUDIT, TEPLAN ISTVAN, MEZO IMRE
Format Patent
LanguageItalian
Published 10.11.1988
Edition4
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to novel gonadoliberine derivatives of the general formula (I) (I) wherein X represents an -O-R group wherein R is a benzyl group or a C1-4 alkyl group, an group wherein R1 and R2 independently stand for hydrogen, a C1-5 alkyl, aryl, aryl-C1-2-alkyl, morpholino, 1-indolinyl or 1-pyrrolidinyl group, Y is a glycine amide or a C1-4-alkyl-amide group, the addition salts thereof formed with acids used in therapy and complexes thereof as well as pharmaceutical compositions containing them, furthermore to a process for the preparation of the above compounds. The reproductive processes of vertebrates can be advantageously influenced with the compounds of general formula (I).
Bibliography:Application Number: IT19840020286