PROCEDIMENTO PER LA PREPARAZIONE DI ETERI OSSIMICI BASICI

An improved process for the preparation of basic oxime ethers of the general Formula I /wherein R is a phenyl group optionally substituted by one to three halogen atom/s/ and/or lower alkoxy group/s/; R and R each are hydrogen or together from a valence bond; A is lower alkylene; R and R each stand...

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Bibliographic Details
Main Authors ARANAK LAY KONYA, KISZELLY ENIKO SZIRT, PETOCZ LUJZA, BUDAI ZOLTAN, MEZEI TIBOR, GRASSER KATALIN
Format Patent
LanguageItalian
Published 10.11.1988
Edition4
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:An improved process for the preparation of basic oxime ethers of the general Formula I /wherein R is a phenyl group optionally substituted by one to three halogen atom/s/ and/or lower alkoxy group/s/; R and R each are hydrogen or together from a valence bond; A is lower alkylene; R and R each stand for hydrogen or lower alkyl or together with the adjacent nitrogen atom they are attached to form a 5-8 membered heterocyclic ring which may optionally contain a further oxygen or nitrogen atom and/or may be optionally substituted by lower alkyl, phenyl or phenyl-lower alkyl, and n is 3, 4, 5, 6 or 7/ and acid addition salts thereof comprises reacting an oxime of the general Formula II with a compound of the general Formula III (where Hal is a halogen atom) or an acid addition salt thereof in the presence of an alkali metal lower alkoxide and an aromatic organic hydrocarbon solvent.
Bibliography:Application Number: IT19840019469