Basískir esterar úr fitu alkóhólum og notkun þeirra sem bólgueyðandi eða ónæmisstýrandi miðlar

Basic esters of fatty alcohols of the general formula: R1-O-CO-A or pharmaceutically acceptable salts thereof, wherein R1 is C12-C24 alkyl or C10-C24 alkenyl, and A is a residue containing at least one acyclic or cyclic amino group and/or at least one heteroaromatic ring containing a tertiary or qua...

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Main Authors JEFFREY STERLING, MEIR SHINITZKY, YAACOV HERZIG, FERENC RANTAL, IRUN R. COHEN, RAANAN MARGALIT, TIVADAR TAMAS, GYORGY TOTH, ISTVAN MISKOLCZI
Format Patent
LanguageIcelandic
Published 31.03.2005
Edition7
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Basic esters of fatty alcohols of the general formula: R1-O-CO-A or pharmaceutically acceptable salts thereof, wherein R1 is C12-C24 alkyl or C10-C24 alkenyl, and A is a residue containing at least one acyclic or cyclic amino group and/or at least one heteroaromatic ring containing a tertiary or quaternary nitrogen atom, are anti-inflammatory and immunomodulatory agents, useful in the treatment of immunologically-mediated inflammation, as adjuvants for antigens involved in both cellular and humoral responses.
Bibliography:Application Number: IS20050007781