Snöggbráðnandi lyfjagjafarform til inntöku um munn

There is provided granules for the production of improved flash-melt pharmaceutical oral dosage forms. In addition to one or more medicaments, the granules are composed of an excipient combination consisting of a superdisintegrant (of two or more agents selected from the group consisting of crospovi...

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Bibliographic Details
Main Authors SANJEEV KOTHARI, DESAI DIVYAKANT
Format Patent
LanguageIcelandic
Published 06.04.2004
Edition7
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:There is provided granules for the production of improved flash-melt pharmaceutical oral dosage forms. In addition to one or more medicaments, the granules are composed of an excipient combination consisting of a superdisintegrant (of two or more agents selected from the group consisting of crospovidone, croscarmellose sodium, sodium, sodium starch glycolate, low-substituted hydroxypropyl cellulose or pregelatinized starch), a dispersing agent, a distributing agent, and a binder and may also include other conventional ingredients such as sweetening and flavoring agents. The subject granules are advantageous in that they are stable and can be prepared without the aid of solvents and without the need for special environments or handling. Dosage forms, especially tablets, prepared therefrom on conventional equipment disintegrate in the mouth in under about twenty five seconds.
Bibliography:Application Number: IS20040007208