THIADIAZOLIDINEDIONES AS GSK 3 INHIBITORS

The present invention relates to new thiadiazolidmediones of formula (I) or any pharmaceutically acceptable salt solvate or prodrug thereof and its use in the treatment of a disease in which glycogen synthase kinase 3 (GSK-3) is involved particularly neurodegenerative diseases inflammatory and autoi...

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Main Authors DOMÍNGUEZ CORREA JUAN MANUEL, RODRÍGUEZ SALGUERO BEATRIZ, MARTÍNEZ MONTERO OLGA, PALOMO NICOLAU FRANCISCO, DE CRISTOBAL BLANCO JAVIER, MEDINA PADILLA MIGUEL, HERRERO SANTOS SUSANA, PÉREZ DE LA CRUZ MORENO MARÍA ÁNGELES, LÓPEZ OGALLA JAVIER, FUERTES HUERTA ANA, SÁNCHEZ QUESADA JORGE
Format Patent
LanguageEnglish
Published 24.04.2015
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention relates to new thiadiazolidmediones of formula (I) or any pharmaceutically acceptable salt solvate or prodrug thereof and its use in the treatment of a disease in which glycogen synthase kinase 3 (GSK-3) is involved particularly neurodegenerative diseases inflammatory and autoimmune diseases and cardiovascular disorders. Additionally there is provided a process for preparing such compounds as well as pharmaceutical compositions comprising them.
Bibliography:Application Number: IN2014DELNP7885