"FLUORO-SUBSTITUTED 3,5-DICYANO-4(1H-INDAZOL-5-YL)-2,6-DIMETHYL-1,4-DIHYDROPYRIDINE DEVIVATIVES AND METHODS OF USE THEREOF"

The present invention relates to novel fluoro-substituted 3,5-dicyano-4-(1H-indazol-5-yl)-2,6-di-methyl-l,4-dihydropyridine derivatives having protein tyrosine kinase inhibitory activity, to a pro¬cess for the manufacture thereof and to the use thereof for the treatment of c-Met-mediated diseases or...

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Main Authors DONALD BIERER, NICOLE TEUSCH, ALEXANDROS VAKALOPOULOS, MARTIN MICHELS, KAREN ENGEL, MARIA KISSEL, MARIO LOBELL, MARKUS FOLLMANN, KATJA ZIMMERMANN
Format Patent
LanguageEnglish
Published 04.09.2015
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention relates to novel fluoro-substituted 3,5-dicyano-4-(1H-indazol-5-yl)-2,6-di-methyl-l,4-dihydropyridine derivatives having protein tyrosine kinase inhibitory activity, to a pro¬cess for the manufacture thereof and to the use thereof for the treatment of c-Met-mediated diseases or c-Met-mediated conditions, particularly cancer and other proliferative disorders.
Bibliography:Application Number: IN2012DELNP2675