Rabies g protein and uses thereof

Provided are polypeptide comprising a rabies G protein ectodomain. The rabies G protein ectodomain may have a deletion of the fusion loop domain. Further provided are nanoparticle vaccines for rabies virus. Further provided are pharmaceutical compositions, methods of manufacturing, and methods of us...

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Bibliographic Details
Main Authors HOLTZMAN Douglas, FELDHAUS Andrew
Format Patent
LanguageEnglish
Hebrew
Published 01.03.2025
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Provided are polypeptide comprising a rabies G protein ectodomain. The rabies G protein ectodomain may have a deletion of the fusion loop domain. Further provided are nanoparticle vaccines for rabies virus. Further provided are pharmaceutical compositions, methods of manufacturing, and methods of use, e.g., immunizing a subject to generate a protective immune response to rabies virus.
Bibliography:Application Number: IL20250318460