Processes for synthesizing glucagon-like-peptide 2 (glp-2) analogues

The present invention relates to processes for obtaining glucagon-like-peptide-2 (GLP-2) analogues, such as glepaglutide. In particular, the processes described herein use a multi-step purification method of GLP-2 analogues synthesized by solid phase peptide synthesis (SPPS).

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Bibliographic Details
Main Authors PAWLAS Jan, MELANDER Claes, MALIK Leila, HANSEN Stefan
Format Patent
LanguageEnglish
Hebrew
Published 01.08.2024
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:The present invention relates to processes for obtaining glucagon-like-peptide-2 (GLP-2) analogues, such as glepaglutide. In particular, the processes described herein use a multi-step purification method of GLP-2 analogues synthesized by solid phase peptide synthesis (SPPS).
Bibliography:Application Number: IL20240313732