Rna encoding peptidoglycan hydrolase and use thereof for treating bacterial infection

The invention provides agents and methods for treating bacterial infections using RNA. The RNA encoding peptidoglycan hydrolases, e.g., endolysins, is formulated and administered in a way that peptidoglycan hydrolase proteins, e.g., endolysin proteins, can be produced and secreted by cells of a subj...

Full description

Saved in:
Bibliographic Details
Main Authors ERBAR Stephanie, VISRAM Zehra, CORSINI Lorenzo, HENNING Andreas, SPIER Anna, SAHIN Ugur, SCHILLE Stefan Albrecht
Format Patent
LanguageEnglish
Hebrew
Published 01.07.2024
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:The invention provides agents and methods for treating bacterial infections using RNA. The RNA encoding peptidoglycan hydrolases, e.g., endolysins, is formulated and administered in a way that peptidoglycan hydrolase proteins, e.g., endolysin proteins, can be produced and secreted by cells of a subject to combat bacterial infections.
Bibliography:Application Number: IL20240312618