Pharmaceutical compositions of an epidermal growth factor receptor inhibitor

The present disclosure relates to pharmaceutical compositions comprising an intragranular phase, wherein the intragranular phase comprises: (i) an amorphous solid dispersion comprising Compound (I) or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable polymer, and (ii) a s...

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Bibliographic Details
Main Authors MAZAIK Debra L, MEDENDORP Clare Aubrey, VAZE Onkar Shripad, KINKEMA Caitlin N
Format Patent
LanguageEnglish
Hebrew
Published 01.02.2024
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present disclosure relates to pharmaceutical compositions comprising an intragranular phase, wherein the intragranular phase comprises: (i) an amorphous solid dispersion comprising Compound (I) or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable polymer, and (ii) a surfactant; and an extragranular phase, wherein the extragranular phase comprises a surfactant. The present disclosure also relates to methods of using said compositions in the treatment of various disorders.
Bibliography:Application Number: IL20230309447