Hard shell capsules with modified release coating

• Main Authors: SMITH Steven, JABER Rima, H?LZER Bettina, NIEPOTH Peter, B?R Hans, HOFMANN Felix
• Format: Patent
• Language: English; Hebrew
• Published: 01.01.2024

The invention refers to a process for preparing a polymer-coated hard shell capsule, wherein the hard shell capsule comprises a body and a cap, wherein in the closed state the cap overlaps the body either in a pre-locked state or in a final-locked state, wherein the hard shell capsule is provided in the pre-locked state and coated with a coating solution, suspension or dispersion comprising or consisting of a) at least one polymer; b) at least one glidant; c) at least one emulsifier; d) optionally at least one plasticizer; e) optionally at least one biologically active ingredient; and f) optionally at least one additive, different from a) to e); to obtain a coated, preferably only at the outer surface, hard shell capsule in the pre-locked state, wherein the coating solution, suspension or dispersion has a surface tension of at most 38 mN/m. Furthermore, the invention refers to a polymer-coated hard shell capsule obtained from the process according to the invention and the use of the polymer-coated hard shell capsule for immediate, delayed or sustained release.