Antibody compositions and methods of use thereof

The disclosure provides pharmaceutical compositions comprising an antibody and at least two antioxidants. In some aspects, pharmaceutical composition is formulated for subcutaneous delivery. In some aspects, the pharmaceutical composition further comprises an endoglycosidase hydrolase enzyme. Other...

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Main Authors KHOSSRAVI Mehrnaz, HART Scott Aaron, HABY Thomas Arthur, MURTHY Bindu Purnima, SANGHAVI Kinjal, ZHAO Xiaochen, BELLO Akintunde, VEZINA Heather Elizabeth, HUANG Masano, ARAS Urvi Ashish, ROY Amit, MANTRI Rao Venkatramana
Format Patent
LanguageEnglish
Hebrew
Published 01.08.2023
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The disclosure provides pharmaceutical compositions comprising an antibody and at least two antioxidants. In some aspects, pharmaceutical composition is formulated for subcutaneous delivery. In some aspects, the pharmaceutical composition further comprises an endoglycosidase hydrolase enzyme. Other aspects of the present disclosure are directed to methods of subcutaneously delivering the pharmaceutical composition.
Bibliography:Application Number: IL20230303648