Heteroaryl substituted pyridines and methods of use

wherein X1, X2, R1, and R2 are as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compound of the in...

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Main Authors KELGTERMANS Hans, GRESZLER Stephen N, ALTENBACH Robert J, BOGDAN Andrew, COTI Ghjuvanni Petru Diunisu, KYM Philip R, VAN DER PLAS Steven Emiel, WANG Xueqing, COWART Marlon D
Format Patent
LanguageEnglish
Hebrew
Published 01.07.2023
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:wherein X1, X2, R1, and R2 are as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compound of the invention.
Bibliography:Application Number: IL20230303196