Preparation of (s)-4-(8-amino-3-(1-but-2-ynoylpyrrolidin-2-yl) imidazo [1,5-a]pyrazin-1-yl)-n-(pyridin-2-yl)benzamide and pharmaceutically acceptable salts thereof

The present invention relates to 6-5 membered fused pyridine ring compounds according to formula Ior a pharmaceutically acceptable salt thereof or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, the present invention relates to the use of 6-5 mem...

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Main Authors STERRENBURG Jan-Gerard, JANS Christiaan Gerardus Johannes Maria, REWINKEL Johannes Bernardus Maria, BARF Tjeerd A, MAN de Adrianus Petrus Antonius, RAAIJMAKERS Hans C.A, WIJKMANS Jacobus C.H.M, OUBRIE Arthur A
Format Patent
LanguageEnglish
Hebrew
Published 01.05.2022
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Summary:The present invention relates to 6-5 membered fused pyridine ring compounds according to formula Ior a pharmaceutically acceptable salt thereof or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, the present invention relates to the use of 6-5 membered fused pyridine ring compounds according to formula I in the treatment of Bruton's Tyrosine Kinase (Btk) mediated disorders.
Bibliography:Application Number: IL20220291489