Anti-viral central memory cd8+ veto cells in haploidentical stem cell transplantation

Methods of generating an isolated population of non-graft versus host disease (GVHD) inducing cells comprising a central memory T-lymphocyte (Tcm) phenotype, the cells being tolerance inducing cells and/or endowed with anti-disease activity, and capable of homing to the lymph nodes following transpl...

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Main Authors Rakefet SIDLIK MUSKATEL, Rotem GIDRON BUDOVSKY, ESTHER BACHAR-LUSTIG, ASSAF LASK, YAIR REISNER, NOGA OR-GEVA
Format Patent
LanguageEnglish
Hebrew
Published 01.04.2022
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Abstract Methods of generating an isolated population of non-graft versus host disease (GVHD) inducing cells comprising a central memory T-lymphocyte (Tcm) phenotype, the cells being tolerance inducing cells and/or endowed with anti-disease activity, and capable of homing to the lymph nodes following transplantation, are disclosed. Cells generated by the methods, pharmaceutical compositions and methods of treatment are also disclosed.
AbstractList Methods of generating an isolated population of non-graft versus host disease (GVHD) inducing cells comprising a central memory T-lymphocyte (Tcm) phenotype, the cells being tolerance inducing cells and/or endowed with anti-disease activity, and capable of homing to the lymph nodes following transplantation, are disclosed. Cells generated by the methods, pharmaceutical compositions and methods of treatment are also disclosed.
Author YAIR REISNER
ASSAF LASK
NOGA OR-GEVA
Rakefet SIDLIK MUSKATEL
ESTHER BACHAR-LUSTIG
Rotem GIDRON BUDOVSKY
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DocumentTitleAlternate תאי ויטו כנגד וירוסים בעלי פנוטיפ של זיכרון מרכזי, ושימוש בהם להשתלת תאי גזע אלוגניים
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ASSAF LASK
NOGA OR-GEVA
YEDA RESEARCH & DEVELOPMENT CO. LTD
Rakefet SIDLIK MUSKATEL
ESTHER BACHAR-LUSTIG
BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM
Rotem GIDRON BUDOVSKY
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Snippet Methods of generating an isolated population of non-graft versus host disease (GVHD) inducing cells comprising a central memory T-lymphocyte (Tcm) phenotype,...
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Title Anti-viral central memory cd8+ veto cells in haploidentical stem cell transplantation
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