Methods of purifying an allergen extract

The invention relates to processes for producing semi-purified and purified allergen extracts and pharmaceutical compositions and vaccines for use in the diagnosis and treatment of allergy. In one aspect of the invention, a process for producing a depigmented allergen extract is provided, the proces...

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Bibliographic Details
Main Authors GALLEGO Maria Teresa, CARNES SANCHEZ Jeronimo, ROMAN-ESCUTIA Marta, MORALES Maria
Format Patent
LanguageEnglish
Hebrew
Published 31.08.2021
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Summary:The invention relates to processes for producing semi-purified and purified allergen extracts and pharmaceutical compositions and vaccines for use in the diagnosis and treatment of allergy. In one aspect of the invention, a process for producing a depigmented allergen extract is provided, the process comprising: a) basifying a native allergen extract; and b) removing molecules having a molecular size of less than 3.5 kDa; and c) adjusting the pH to neutrality; thereby to produce a depigmented allergen extract.
Bibliography:Application Number: IL20210284901