Replication competent oncolytic group b adenovirus
A replication competent oncolytic group B adenovirus EnAd comprising: two or more transgenes, a first transgene comprising a DNA sequence encoding B7-1 protein, and an additional transgene encoding an anti-CD3 antibody or binding fragment thereof, pharmaceutical compositions comprising said virus an...
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Main Authors | , |
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Format | Patent |
Language | English Hebrew |
Published |
01.07.2022
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Subjects | |
Online Access | Get full text |
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Summary: | A replication competent oncolytic group B adenovirus EnAd comprising: two or more transgenes, a first transgene comprising a DNA sequence encoding B7-1 protein, and an additional transgene encoding an anti-CD3 antibody or binding fragment thereof, pharmaceutical compositions comprising said virus and use of any one of the same in treatment, in particular the treatment of cancer. |
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Bibliography: | Application Number: IL20210284375 |