System and methods for engineering bacteria fit for eukaryotic mrna production, export, and translation in a eukaryotic host

The inventive technology includes novel systems, methods, and compositions for the generation of genetically engineered prokaryotic organisms configured to produce eukaryotic-like mRNA that may be introduced to, and translated in a eukaryotic host. Additional aspects may include novel eukaryotic-lik...

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Bibliographic Details
Main Authors YIN Dr. Guohua, SAYRE Richard, COSTA-NUNES Pedro
Format Patent
LanguageEnglish
Hebrew
Published 01.03.2021
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Summary:The inventive technology includes novel systems, methods, and compositions for the generation of genetically engineered prokaryotic organisms configured to produce eukaryotic-like mRNA that may be introduced to, and translated in a eukaryotic host. Additional aspects may include novel eukaryotic-like nucleotide constructs and mRNA molecules, as well as methods and systems for the efficient delivery from prokaryotic cells to target eukaryotic hosts cells. Still further aspects of the invention include systems, methods and compositions for the the non-integrative transformation of eukaryotic cell.
Bibliography:Application Number: IL20200279874