Antibodies targeting a galactan-based o-antigen of k. pneumoniae

The invention provides for an isolated antibody that specifically recognizes a galactan-III epitope of the lipopolysaccharide (LPS) O-antigen structure of Klebsiella pneumoniae, which epitope is incorporated in galactan-III repeating units, wherein the galactan-III repeating unit is a branched galac...

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Bibliographic Details
Main Authors SZIJARTO VALERIA, Zehra VISRAM, NAGY GABOR, LUKASIEWICZ JOLANTA, ESZTER NAGY, GUACHALLA LUIS
Format Patent
LanguageEnglish
Hebrew
Published 31.10.2017
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Summary:The invention provides for an isolated antibody that specifically recognizes a galactan-III epitope of the lipopolysaccharide (LPS) O-antigen structure of Klebsiella pneumoniae, which epitope is incorporated in galactan-III repeating units, wherein the galactan-III repeating unit is a branched galactose homopolymer of Formula (I). The invention further provides for a pharmaceutical or diagnostic preparation comprising said antibody, and a method of producing said antibody.
Bibliography:Application Number: IL20170253920