Diamino heterocyclic carboxamide compounds, use thereof and pharmaceutical compositions and inhibitors comprising them

Provided is the compound 6-ethyl-3-({3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}amino)-5-(tetrahydro-2H-pyran-4-ylamino)pyrazine-2-carboxamide or a salt thereof for use in a method for preventing and/or treating acute myelocytic leukemia or atypical chronic myelocytic leukemia.

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Main Authors KAZUHIKO IIKUBO, YOSHINORI IWAI, HIROSHI TOMIYAMA, KAZUO KUROSAWA, TAKAHIRO MATSUYA, ITSURO SHIMADA, YUTAKA KONDOH, AKIO KAMIKAWA
Format Patent
LanguageEnglish
Hebrew
Published 29.10.2015
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract Provided is the compound 6-ethyl-3-({3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}amino)-5-(tetrahydro-2H-pyran-4-ylamino)pyrazine-2-carboxamide or a salt thereof for use in a method for preventing and/or treating acute myelocytic leukemia or atypical chronic myelocytic leukemia.
AbstractList Provided is the compound 6-ethyl-3-({3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}amino)-5-(tetrahydro-2H-pyran-4-ylamino)pyrazine-2-carboxamide or a salt thereof for use in a method for preventing and/or treating acute myelocytic leukemia or atypical chronic myelocytic leukemia.
Author KAZUO KUROSAWA
HIROSHI TOMIYAMA
TAKAHIRO MATSUYA
KAZUHIKO IIKUBO
YOSHINORI IWAI
ITSURO SHIMADA
YUTAKA KONDOH
AKIO KAMIKAWA
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– fullname: ITSURO SHIMADA
– fullname: YUTAKA KONDOH
– fullname: AKIO KAMIKAWA
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HIROSHI TOMIYAMA
TAKAHIRO MATSUYA
KAZUHIKO IIKUBO
YOSHINORI IWAI
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YUTAKA KONDOH
AKIO KAMIKAWA
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HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title Diamino heterocyclic carboxamide compounds, use thereof and pharmaceutical compositions and inhibitors comprising them
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