Diamino heterocyclic carboxamide compounds, use thereof and pharmaceutical compositions and inhibitors comprising them

Provided is the compound 6-ethyl-3-({3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}amino)-5-(tetrahydro-2H-pyran-4-ylamino)pyrazine-2-carboxamide or a salt thereof for use in a method for preventing and/or treating acute myelocytic leukemia or atypical chronic myelocytic leukemia.

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Bibliographic Details
Main Authors KAZUHIKO IIKUBO, YOSHINORI IWAI, HIROSHI TOMIYAMA, KAZUO KUROSAWA, TAKAHIRO MATSUYA, ITSURO SHIMADA, YUTAKA KONDOH, AKIO KAMIKAWA
Format Patent
LanguageEnglish
Hebrew
Published 29.10.2015
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Provided is the compound 6-ethyl-3-({3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}amino)-5-(tetrahydro-2H-pyran-4-ylamino)pyrazine-2-carboxamide or a salt thereof for use in a method for preventing and/or treating acute myelocytic leukemia or atypical chronic myelocytic leukemia.
Bibliography:Application Number: IL20110216132