PROCESS FOR PREPARING (1R,2S,4R) - (-) - 2 - [2(2' - {N,N - DIMETHYLAMINO} - ETHOXY)] - 2 - [PHENYL1 ] - 1,7,7 - TRI - [METHYL] - BICYCLO [2.2.1] HEPTANE

The invention relates to high purity (1R,2S,4R)-(-)-2-[(2'-{N,N-dimethylamino}-ethoxy)]-2-[phenyl]-1,7,7-tri-[methyl]-bicyclo[2.2.1]heptane and pharmaceutically acceptable acid addition salts thereof containing not more than 0.2% of (1R,3S,4R)-3-[(2'-{N,N-dimethylamino}-ethyl)]-1,7,7-tri-[...

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Main Authors TIBOR MEZEI, ZOLTAN BUDAI, JANOS SZYLAGYI, GYULA LUKACS, GYORGYI DONATH VERECZKEY, GYULA SIMIG, MARTA PORCS-MAKKAY, GYORGEY KRASZNAI, KALMAN NAGY, NORBERT NEMETH, TIBOR SZABO
Format Patent
LanguageEnglish
Published 26.11.2008
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Summary:The invention relates to high purity (1R,2S,4R)-(-)-2-[(2'-{N,N-dimethylamino}-ethoxy)]-2-[phenyl]-1,7,7-tri-[methyl]-bicyclo[2.2.1]heptane and pharmaceutically acceptable acid addition salts thereof containing not more than 0.2% of (1R,3S,4R)-3-[(2'-{N,N-dimethylamino}-ethyl)]-1,7,7-tri-[methyl]-bicyclo[2.2.1]heptane-2-one and/or of a pharmaceutically acceptable acid addition salt thereof.Furthermore the invention is concerned with a process for the preparation of these compounds.Moreover the invention relates to medicaments containing 1 or more of these compounds and their use.
Bibliography:Application Number: IL20010146421