CHROMATOGRAPHIC PROCESS FOR THE PURIFICATION OF GLYCOPROTEINS

The present invention is directed to a simple and efficient process for the recovery of a biologically active glycoprotein from a biological fluid containing it. It includes a phenyl boronate chromatography step and is particularly suitable for the purification of erythropoietin.

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Bibliographic Details
Main Authors EDOARDO GIACOMO SARUBBI, EMENEGILDO RESTELLI, AMANDO GRIGOLETTO, ADOLFO SOFFIENTINI, DINO ZANETTE
Format Patent
LanguageEnglish
Published 25.07.2002
Edition7
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES USING MICROORGANISMS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The present invention is directed to a simple and efficient process for the recovery of a biologically active glycoprotein from a biological fluid containing it. It includes a phenyl boronate chromatography step and is particularly suitable for the purification of erythropoietin.
Bibliography:Application Number: IL19960117849