A new antimicrobial agent, fr109615 and production thereof

• Main Authors: MIYAUCHI MICHIYO, OKUHARA MASAKUNI, TSUJII EISAKU, HASHIMOTO HIDEO, EZAKI MASAMA
• Format: Patent
• Language: English
• Published: 14.12.1994
• Edition: 5
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; AGRICULTURE; ANIMAL HUSBANDRY; BEER; BIOCHEMISTRY; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; CHEMISTRY; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; FISHING; FORESTRY; HUMAN NECESSITIES; HUNTING; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF; PROCESSES USING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; TRAPPING; VINEGAR; WINE

The invention relates to a new anti-microbial compound, designated FR109615, having the characteristics and physico-chemical properties described herein. The compound shows anti-microbial activity against pathogenic microorganisms, especially pathogenic fungi, and is useful for the treatment of various infectious diseases in both human beings and animals. There is provided a process for preparing the FR109615 compound which comprises culturing a FR109615 producing strain belonging to the genus Steptomyces in a nutrient medium. Pharmaceutical compositions comprising FR109615 as an active ingredient are also described.