PROCESS FOR PRODUCING COMPOSITION SUITABLE FOR TREATING INFECTIONS CAUSED BY ORGANISMS SENSITIVE TO BETA-LACTAM ANTIBIOTICS

The invention is directed to compositions and methods for treating an infection caused by an organism susceptible to a beta -lactam antibiotic comprising two or more active agents. In one embodiment, the composition comprises: (1) a beta -lactam antibiotic and (2) a cationic oligopeptide. In another...

Full description

Saved in:
Bibliographic Details
Main Authors COSAND,WESLEY L.,US, DARVEAU,RICHARD P.,US, BLAKE,JAMES J.,US
Format Patent
LanguageEnglish
Published 28.09.1993
Edition5
Subjects
Online AccessGet full text

Cover

Loading…
Abstract The invention is directed to compositions and methods for treating an infection caused by an organism susceptible to a beta -lactam antibiotic comprising two or more active agents. In one embodiment, the composition comprises: (1) a beta -lactam antibiotic and (2) a cationic oligopeptide. In another embodiment, the invention is also directed to a composition comprising: (1) a beta -lactam antibiotic which inhibits the growth of Enterobacteriaceae bacteria and (2) at least one membrane active substance. Further, the invention is also directed to improved methods for screening potential bactericidal compositions in vitro wherein components of an active complement cascade are included.
AbstractList The invention is directed to compositions and methods for treating an infection caused by an organism susceptible to a beta -lactam antibiotic comprising two or more active agents. In one embodiment, the composition comprises: (1) a beta -lactam antibiotic and (2) a cationic oligopeptide. In another embodiment, the invention is also directed to a composition comprising: (1) a beta -lactam antibiotic which inhibits the growth of Enterobacteriaceae bacteria and (2) at least one membrane active substance. Further, the invention is also directed to improved methods for screening potential bactericidal compositions in vitro wherein components of an active complement cascade are included.
Author DARVEAU,RICHARD P.,US
BLAKE,JAMES J.,US
COSAND,WESLEY L.,US
Author_xml – fullname: COSAND,WESLEY L.,US
– fullname: DARVEAU,RICHARD P.,US
– fullname: BLAKE,JAMES J.,US
BookMark eNqFy70OgkAQBGAKLfx7BbMvQEXEejkW2ATuCLuYWBFizsoACXa-vGLsrWaS-WYbrIZx8JvgVTfOkAhkroFPT1vDNgfjqtoJKzsL0rJiUtKXaEOoi2CbkVl2AYOtUArJFVyTo2WpBITscr8QqIOEFMMSjWIFaJUTdspG9sH63j9mf_jlLjhmpKYI_TR2fp76mx_8sytajaNTfMboL3gDvDg8OQ
ContentType Patent
DBID EVB
DatabaseName esp@cenet
DatabaseTitleList
Database_xml – sequence: 1
  dbid: EVB
  name: esp@cenet
  url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP
  sourceTypes: Open Access Repository
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
Chemistry
Sciences
Edition 5
ExternalDocumentID HUT63567A
GroupedDBID EVB
ID FETCH-epo_espacenet_HUT63567A3
IEDL.DBID EVB
IngestDate Fri Jul 19 14:57:58 EDT 2024
IsOpenAccess true
IsPeerReviewed false
IsScholarly false
Language English
LinkModel DirectLink
MergedId FETCHMERGED-epo_espacenet_HUT63567A3
Notes Application Number: HU19920002720
OpenAccessLink https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19930928&DB=EPODOC&CC=HU&NR=T63567A
ParticipantIDs epo_espacenet_HUT63567A
PublicationCentury 1900
PublicationDate 19930928
PublicationDateYYYYMMDD 1993-09-28
PublicationDate_xml – month: 09
  year: 1993
  text: 19930928
  day: 28
PublicationDecade 1990
PublicationYear 1993
RelatedCompanies BRISTOL-MYERS SQUIBB CO.,US
RelatedCompanies_xml – name: BRISTOL-MYERS SQUIBB CO.,US
Score 2.4327986
Snippet The invention is directed to compositions and methods for treating an infection caused by an organism susceptible to a beta -lactam antibiotic comprising two...
SourceID epo
SourceType Open Access Repository
SubjectTerms CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title PROCESS FOR PRODUCING COMPOSITION SUITABLE FOR TREATING INFECTIONS CAUSED BY ORGANISMS SENSITIVE TO BETA-LACTAM ANTIBIOTICS
URI https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19930928&DB=EPODOC&locale=&CC=HU&NR=T63567A
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwdV05T8MwFLZKQcAG5T4qDyhbRNqkOYYIOY7TBDWHYqcqU0WOIpa2okEM_HnskAILm-XjSX7SO2y_7zMAd0apiJxNlw1LqWStyMVvgKYiKzl3fbpRlouRwA6Hke5n2uNsNOuAly0WpuEJ_WjIEblFFdze68Zfr38vsdymtnJzn7_yrtWDx2xXKlu4mKpYQ1NyHZsksRtjCWPbz6QotZngYTPQDtgVObQg2SdTR0BS1n_jiXcE9hIualkfg0617IEDvP12rQf2w_a1mzdbw9ucgM8kjTHXFeSHNsjbboaDaAxxHCYxDcQ1E6RZwJAzIc0UlhLExIwg8khTJ0IhRhklLnSeYJyOURTQkEJKIrF8SiCLoUMYkicIMxRCFLHACWIWYHoK-h5h2Jf5LuY_-pr7Wbtb9Qx0l6tldQFgbpRqrgyqUtdMzXrWrIGqV6pgu1IXo6LIL8H5P0Ku_h25Boff5X-WPDRvQLd-e69ueYiu836j3i_vwY3m
link.rule.ids 230,309,786,891,25594,76903
linkProvider European Patent Office
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwdR3LTsMwLBoDMW4w3o-RA-qtolu7dj1MKE3TNdCX1nQap4k-hrh0EyviwM-TlA247BYljiVbsh07fgBwZ-SKeLPpsmEqhaxlqZgGOFBkJeWqTzfyfN4XtcN-oLuJ9jjtTxvgdVMLU_cJ_aybI3KJyri8V7W-Xv4Fsew6t3J1n77xrcWDw4a2lK_LxVTF7A0k2xqSKLRDLGE8dBMpGA-Z6MNmoB2wa3B_sPaTJpYoSVn-tyfOIdiLOKqyOgKNomyDFt6MXWuDfX_9282Xa8FbHYOvaBxizivInTbI13aCaTCCOPSjMKYizATjhDJkeaQGYWOCmICggUPqPJEYYpTExIbWMwzHIxTQ2I9hTAJxfUIgC6FFGJI9hBnyIQoYtWjIKI5PQMchDLsyp2L2y6-Zm6ypVU9Bs1yUxTmAqZGrqdItcl0baOaLZnZVvVBFtyt13s-y9AKcbUFyufXkFrRc5nszjwZPV-DgJxXQlHuDa9Cs3j-KG26uq7RTs_obtqKQ0A
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=PROCESS+FOR+PRODUCING+COMPOSITION+SUITABLE+FOR+TREATING+INFECTIONS+CAUSED+BY+ORGANISMS+SENSITIVE+TO+BETA-LACTAM+ANTIBIOTICS&rft.inventor=COSAND%2CWESLEY+L.%2CUS&rft.inventor=DARVEAU%2CRICHARD+P.%2CUS&rft.inventor=BLAKE%2CJAMES+J.%2CUS&rft.date=1993-09-28&rft.externalDBID=A&rft.externalDocID=HUT63567A