PROCESS FOR PRODUCING COMPOSITION SUITABLE FOR TREATING INFECTIONS CAUSED BY ORGANISMS SENSITIVE TO BETA-LACTAM ANTIBIOTICS
The invention is directed to compositions and methods for treating an infection caused by an organism susceptible to a beta -lactam antibiotic comprising two or more active agents. In one embodiment, the composition comprises: (1) a beta -lactam antibiotic and (2) a cationic oligopeptide. In another...
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| Main Authors | , , |
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| Format | Patent |
| Language | English |
| Published |
28.09.1993
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| Edition | 5 |
| Subjects | |
| Online Access | Get full text |
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| Abstract | The invention is directed to compositions and methods for treating an infection caused by an organism susceptible to a beta -lactam antibiotic comprising two or more active agents. In one embodiment, the composition comprises: (1) a beta -lactam antibiotic and (2) a cationic oligopeptide. In another embodiment, the invention is also directed to a composition comprising: (1) a beta -lactam antibiotic which inhibits the growth of Enterobacteriaceae bacteria and (2) at least one membrane active substance. Further, the invention is also directed to improved methods for screening potential bactericidal compositions in vitro wherein components of an active complement cascade are included. |
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| AbstractList | The invention is directed to compositions and methods for treating an infection caused by an organism susceptible to a beta -lactam antibiotic comprising two or more active agents. In one embodiment, the composition comprises: (1) a beta -lactam antibiotic and (2) a cationic oligopeptide. In another embodiment, the invention is also directed to a composition comprising: (1) a beta -lactam antibiotic which inhibits the growth of Enterobacteriaceae bacteria and (2) at least one membrane active substance. Further, the invention is also directed to improved methods for screening potential bactericidal compositions in vitro wherein components of an active complement cascade are included. |
| Author | DARVEAU,RICHARD P.,US BLAKE,JAMES J.,US COSAND,WESLEY L.,US |
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| Notes | Application Number: HU19920002720 |
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| Snippet | The invention is directed to compositions and methods for treating an infection caused by an organism susceptible to a beta -lactam antibiotic comprising two... |
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| SubjectTerms | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| Title | PROCESS FOR PRODUCING COMPOSITION SUITABLE FOR TREATING INFECTIONS CAUSED BY ORGANISMS SENSITIVE TO BETA-LACTAM ANTIBIOTICS |
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