PROCESS FOR PRODUCING PYRANOBENZOXADIAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING SUCH COMPOUNDS

The invention includes compounds of the formula (I): wherein A represents OH or OC(O)CH3-nXn, B represents hydrogen atom, or A and B together represent a bond; R represents hydrogen atom, R represents hydrogen atom, C(Z)CH3-nXn or C(Z)NHCH3-nXn or R and R together represents (CH2)m, (CH2)m-1C(Z), N(...

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Main Authors OHRAI,KAZUHIKO,JP, MASUDA,YUKINORI,JP, MATSUMOTO,HIROO,JP, SETO,KIYOTOMO,JP, SAKODA,RYOZO,JP, KAMIKAWAJI,YOSHIMASA,JP, NAKAYAMA,KYOKO,JP
Format Patent
LanguageEnglish
Published 28.08.1991
Edition5
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention includes compounds of the formula (I): wherein A represents OH or OC(O)CH3-nXn, B represents hydrogen atom, or A and B together represent a bond; R represents hydrogen atom, R represents hydrogen atom, C(Z)CH3-nXn or C(Z)NHCH3-nXn or R and R together represents (CH2)m, (CH2)m-1C(Z), N(R )(CH2)2C(Z), (CH2)m-2NHC(Z) or (CH2)m-2OC(Z) in which X represents fluorine atom, chlorine atom, bromine atom, a methyl group or a methoxy group and n represents 0 or an integer of 1 to 3, Z represents oxygen atom or sulfur atom, m represents an integer of 4 or 5 and R represents hydrogen atom or a methyl group, and pharmacological acceptable salts of the compounds which can form salts, preparation methods therefor, pharmaceutical use of the compounds and compositions comprising the compounds.
Bibliography:Application Number: HU19890001051