PROCESS FOR CONSTRUCTION OF ASPERGILLUS STRAINS BY GENE SUBSTITUTION

Transformation of Aspergillus, particularly A. niger is demonstrated. Integration at the glucoamylase locus is exemplified. A chymosin expression construct is inserted at a locus, where the chymosin may be joined to a signal sequence for efficient secretion.

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Bibliographic Details
Main Authors VAN DEN BERG,JOHANNES A.,NL, VAN HARTINGSVELDT,WIM,NL, VAN DEN HONDEL,CEES A.,NL, VEENSTRA,ANNEMARIE E.,NL
Format Patent
LanguageEnglish
Published 28.04.1990
Edition5
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
DERIVATIVES THEREOF
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES USING MICROORGANISMS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
SUGARS
VINEGAR
WINE
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Summary:Transformation of Aspergillus, particularly A. niger is demonstrated. Integration at the glucoamylase locus is exemplified. A chymosin expression construct is inserted at a locus, where the chymosin may be joined to a signal sequence for efficient secretion.
Bibliography:Application Number: HU19890004197