PROCESS FOR PRODUCING SUBSTITUTED PYRROL DERIVATIVES
3-[ omega -(3,5-Di-t-butyl-4-hydroxyphenyl)alkanoyl]pyrroles and their de-oxy analogs, for example, 3-(3,5-di-t-butyl-4-hydroxybenzyl)pyrrole, 2-chloro-4-(3,5-di-t-butyl-4-hydroxybenzoyl)pyrrole, 3-(3,5-di-t-butyl-4-hydroxybenzoyl)pyrrole and 3-[2-(3,5-di-t-butyl-4-hydroxyphenyl)-1-oxoethyl]pyrrole,...
Saved in:
Main Authors | , , , , , , |
---|---|
Format | Patent |
Language | English |
Published |
28.04.1989
|
Edition | 4 |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | 3-[ omega -(3,5-Di-t-butyl-4-hydroxyphenyl)alkanoyl]pyrroles and their de-oxy analogs, for example, 3-(3,5-di-t-butyl-4-hydroxybenzyl)pyrrole, 2-chloro-4-(3,5-di-t-butyl-4-hydroxybenzoyl)pyrrole, 3-(3,5-di-t-butyl-4-hydroxybenzoyl)pyrrole and 3-[2-(3,5-di-t-butyl-4-hydroxyphenyl)-1-oxoethyl]pyrrole, are useful for the treatment of psoriasis or other allergic conditions such as conjunctivitis, bronchial asthma and inflammatory bronchial diseases; inflammatory bowel disease; inflammatory diseases; as analgesic and antipyretic agents; in bone diseases such as osteoporosis, periodontitis, tumor-related hypercalcemia, osteopetrosis, and Paget's Disease; and in ischemic heart disease including myocardial ischemia and myocardial infarction. |
---|---|
Bibliography: | Application Number: HU19870004130 |