PROCESS FOR PRODUCING NEW DIPHENYL-PROPYLAMINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING SUCH COMPOUNDS

Diphenylpropylamine derivatives of the formula I in which: R denotes hydrogen or methyl, R denotes hydrogen, methyl or n-decyl, Z (a) denotes a phenyl group substituted by R , R and R , in which: R denotes hydrogen, fluorine, chlorine or bromine, nitro, C1-12-alkyl, C1-4-alkoxy, phenoxy or benzyloxy...

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Main Authors BATA,IMRE,HU, KORBONITS,DEZSOE,HU, KOVACS,GABOR,HU, UDVARI,EVA,HU, SANTANE CSUTOR,ANDREA,HU, VARGAI,ZOLTAN,HU, VIRAG,SANDOR,HU, KOERMOECZY,PETER,HU, MARMAROSI,TAMASNE,HU, PAPP,GYULA,HU, TARDOS,LASZLO,HU, GERGELY,VERA,HU, KISS,PAL,HU, SZEKERES,LASZLO,HU
Format Patent
LanguageEnglish
Published 28.11.1988
Edition4
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Diphenylpropylamine derivatives of the formula I in which: R denotes hydrogen or methyl, R denotes hydrogen, methyl or n-decyl, Z (a) denotes a phenyl group substituted by R , R and R , in which: R denotes hydrogen, fluorine, chlorine or bromine, nitro, C1-12-alkyl, C1-4-alkoxy, phenoxy or benzyloxy, R and R denotes hydrogen, chlorine, hydroxyl, alkoxy, benzyloxy, acetamido or carboxyl or R and R together denote methylenedioxy or (b) denotes 4-methoxynaphthyl or 4-ethoxynaphthyl, and R denotes hydrogen or fluorine, with the proviso that R , R , R , R , R and R do not simultaneously denote hydrogen atoms, and their physiologically tolerable acid addition salts are used as active substances in pharmaceutical agents which can primarily be advantageously used for the therapy of cardiac and circulatory disorders.
Bibliography:Application Number: HU19860002873