PROCESS FOR PRODUCING NEW, SUBSTITUTED ANILIDE DERIVATIVES

The invention relates to new substituted dihydropyridine derivatives of the general formula (I), wherein R1 and R6 are as defined herein after, the racemic and optically active variants as well as mixtures thereof, furthermore the acid addition salts of these compounds, pharmaceutical compositions c...

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Bibliographic Details
Main Authors LANG,TIVADARNE,HU, BORSY,JOZSEF,HU, HORVATH,GYULA,HU, RABLOCZKY,GYOERGY,HU, CZOLLNER,LASZLO,HU, NAGYNE CSOKAS,GYOENGYI,HU, VARRO,ANDRAS,HU, BODI,ILONA,HU, BOZO,EVA,HU, ELEKES,ISTVAN,HU, SZILAGYI,GEZA,HU, CSEH,GYOERGY,HU, JASZLITS,LASZLO,HU
Format Patent
LanguageEnglish
Published 28.07.1988
Edition4
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to new substituted dihydropyridine derivatives of the general formula (I), wherein R1 and R6 are as defined herein after, the racemic and optically active variants as well as mixtures thereof, furthermore the acid addition salts of these compounds, pharmaceutical compositions containing the same and a process for the preparation thereof. The compounds of the general formula (I) can be advantageously applied for the treatment of pathologically severe hypertensions, their toxicity is low and they possess an advantageous therapeutic index.
Bibliography:Application Number: HU19860003948